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Safety of Fluoride: all sources
The main safety issue is chronic fluoride intake from all sources during tooth development years (less than 8 years of age) and enamel fluorosis
Recommendations
refine fluoridated toothpaste to lower the risk of fluorosis without significantly reducing its effectiveness in caries prevention.
encourage commencement of toothpaste use in the 19- to 30-month age period
use of 400- to 550-ppm fluoridated toothpaste when toothpaste use starts
encourage spitting after brushing
prevent an eating/licking toothpaste habit in young children.