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Water fluoridation and Sealants
Prospective (mean 2 years) cohort study of children in Australia
789 children (mean age = 10.5 years) with one sealed permanent first molar at baseline, while the paired surface was diagnosed as sound.
The caries incidence of the fissure sealed occlusal surfaces was 5.6% compared to 11.1% for sound surfaces (p < 0.001); a 50% reduction in caries incidence for sealed vs non-sealed surfaces.